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HTA of MDs
Health Technology Assessment of Medical Devices


HTA is multi-disciplinary field of policy analysis that examines the medical, economic, social and ethical implications of the incremental value, diffusion and use of a health technology in health care.

The term Health Technology refers to application of organised knowledge and skills in the form of devices, medicines, vaccines, procedures and systems developed to solve a health problem and improve quality of life.



Library of Assessments on MDs (1999-2020)

50 Entries into category "other"

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Perceval S sutureless valve for aortic valve replacement: a review of the clinical effectiveness, safety, and cost-effectiveness

Research Questions: What is the clinical effectiveness and safety of the Perceval S sutureless valve for patients requiring aortic valve replacement? What is the cost-effectiveness of the Perceval S sutureless valve for patients requiring aortic valve replacement? Key Findings: Based on preliminary results from single-arm studies and small non-randomized comparisons with alternative methods for valve replacement, […]

The cost-effectiveness of domiciliary non-invasive ventilation in patients with end-stage chronic obstructive pulmonary disease: a systematic review and economic evaluation

Chronic obstructive pulmonary disease (COPD) is a chronic progressive lung disease characterised by non-reversible airflow obstruction. Exacerbations are a key cause of morbidity and mortality and place a considerable burden on health-care systems. While there is evidence that patients benefit from non-invasive ventilation (NIV) in hospital during an acute exacerbation, evidence supporting home use for more stable COPD patients is […]

Transoral Robotic Surgery: A Review of Clinical and Cost-Effectiveness

RESEARCH QUESTIONS  1. What is the clinical effectiveness of TORS for patients with early stage oral or oropharyngeal cancer?  2. What is the clinical effectiveness of TORS for patients with OSA?  3. What is the cost-effectiveness of TORS for patients with early stage oral or oropharyngeal cancer?  4. What is the cost-effectiveness of TORS for patients […]

Total hip replacement and surface replacement for the treatment of pain and disability resulting from end-stage arthritis of the hip (review of technology appraisal guidance 2 and 44): systematic review and economic evaluation

Total hip replacement (THR) involves the replacement of a damaged hip joint with an artificial hip prosthesis. Resurfacing arthroplasty (RS) involves replacement of the joint surface of the femoral head with a metal surface covering. The objective of this review was to undertake clinical effectiveness and cost-effectiveness analysis of different types of THR and RS for the treatment of pain […]

Methods of international health technology assessment agencies for economic evaluations- a comparative analysis

Abstract Background: The number of Health Technology Assessment (HTA) agencies increases. One component of HTAs are economic aspects. To incorporate economic aspects commonly economic evaluations are performed. A convergence of recommendations for methods of health economic evaluations between international HTA agencies would facilitate the adaption of results to different settings and avoid unnecessary expense. A first step in this direction […]

Transcatheter aortic valve implantation: Evaluation of the evidence and synthesis of organizational issues

Aortic valvular stenosis, or narrowing of the valve orifice, is a progressive disease that generally affects patients over the age of 65 years in Western countries and is usually caused by degenerative calcification. Aortic stenosis causes increasing resistance against the ejection of blood from the left ventricle towards the aorta. After symptoms appear (dyspnea, angina, syncope), […]

Multi-criteria decision analysis for health technology assessment in Canada: Insights from an expert panel discussion

Multi-criteria decision analysis (MCDA), a decision-making tool, has received increasing attention in recent years, notably in the healthcare field. For Canada, it is unclear whether and how MCDA should be incorporated into the existing health technology assessment (HTA) decision-making process. To facilitate debate on improving HTA decision-making in Canada, a workshop was held in conjunction with […]

International survey of methods used in health technology assessment (HTA): does practice meet the principles proposed for good research?

Objective: To describe research methods used internationally in health technology assessment (HTA) and health-care reimbursement policies; compare the survey findings on research methods and processes to published HTA principles; and discuss important issues/trends reported by HTA bodies related to current research methods and applications of the HTA process. Methods: Representatives from HTA bodies worldwide were recruited […]

Transcatheter Aortic Valve Implantation (TAVI): a Health Technology Assessment Update

Transcatheter Aortic Valve Insertion – TAVI – is a technique involving the implantation of an artificial valve into a narrowed aortic valve without the need to stop the heart. There are two variants of this procedure. In the first, the artificial valve is inserted through an artery, generally the femoral artery, in which case it is called a «transfemoral TAVI». […]

Colombian Health System on its Way to Improve Allocation Efficiency—Transition from a Health Sector Reform to the Settlement of an HTA Agency

Over the past 20 years, Colombia has invested major efforts in ensuring universal health care access to its citizens while facing epidemiological transition and demographic changes. The country, as any other region in the world, is challenged by financial constraints and market pressures for entry of new and frequently costly technol- ogies. After the 1993 health […]