HTA is multi-disciplinary field of policy analysis that examines the medical, economic, social and ethical implications of the incremental value, diffusion and use of a health technology in health care.
The term Health Technology refers to application of organised knowledge and skills in the form of devices, medicines, vaccines, procedures and systems developed to solve a health problem and improve quality of life.
Abstract Background Surgical aortic valve replacement (SAVR) is the conventional treatment in patients at low or intermediate surgical risk. Transcatheter aortic valve implantation (TAVI) is a less invasive procedure, originally developed as an alternative for patients at high or prohibitive surgical risk. Methods We conducted a health technology assessment of TAVI versus SAVR in patients with […]
Transcatheter aortic valve implantation (TAVI), also referred to as transcatheter aortic valve replacement (TAVR), is the deployment of a bioprosthesis in the aortic valve using a catheter. In contrast to traditional open-heart surgery (i.e. surgical aortic valve replacement, SAVR), the procedure is minimally invasive when performed through transfemoral access and can be performed with light sedation […]
The aortic valve is one of four valves in the heart. It allows blood to flow from the left ventricle of the heart into the aorta (the main artery in the body). Aortic valve stenosis occurs if the valve narrows and cannot open all the way, partially blocking the flow of blood out of the heart. […]
Research Questions: What is the clinical effectiveness and safety of the Perceval S sutureless valve for patients requiring aortic valve replacement? What is the cost-effectiveness of the Perceval S sutureless valve for patients requiring aortic valve replacement? Key Findings: Based on preliminary results from single-arm studies and small non-randomized comparisons with alternative methods for valve replacement, […]
Transcatheter Aortic Valve Insertion – TAVI – is a technique involving the implantation of an artificial valve into a narrowed aortic valve without the need to stop the heart. There are two variants of this procedure. In the first, the artificial valve is inserted through an artery, generally the femoral artery, in which case it is called a «transfemoral TAVI». […]
Transcatheter aortic valve implantation (TAVI) has become an alternative to surgical aortic valve replacement (sAVR) for patients at high risk for surgery. The objective of this analysis is to evaluate the safety, effectiveness, and cost-effectiveness of transcatheter aortic valve implantation (TAVI) for treatment of aortic valve stenosis (AVS) in symptomatic older adults. AVS can result from the progressive build-up […]
Aortic valvular stenosis, or narrowing of the valve orifice, is a progressive disease that generally affects patients over the age of 65 years in Western countries and is usually caused by degenerative calcification. Aortic stenosis causes increasing resistance against the ejection of blood from the left ventricle towards the aorta. After symptoms appear (dyspnea, angina, syncope), […]