HTA is multi-disciplinary field of policy analysis that examines the medical, economic, social and ethical implications of the incremental value, diffusion and use of a health technology in health care.
The term Health Technology refers to application of organised knowledge and skills in the form of devices, medicines, vaccines, procedures and systems developed to solve a health problem and improve quality of life.
The future promises many technological advances in the field of heart valve interventions, like tissue-engineered heart valves (TEHV). Prior to introduction in clinical practice, it is essential to perform early health technology assessment. We aim to develop a conceptual model (CM) that can be used to investigate the performance and costs requirements for TEHV to become cost-effective.
Research Questions: What is the clinical effectiveness and safety of the Perceval S sutureless valve for patients requiring aortic valve replacement? What is the cost-effectiveness of the Perceval S sutureless valve for patients requiring aortic valve replacement? Key Findings: Based on preliminary results from single-arm studies and small non-randomized comparisons with alternative methods for valve replacement, […]
This Health Technology Assessment report summarises current evidence supporting the use of percutaneous heart valves in degenerative aortic valve and congenital pulmonary outflow tract disease, as compared to conservative medical therapy or traditional surgical valve replacement. Percutaneous aortic valve insertion has been reported since 2002 for the treatment of calcific aortic valve stenosis in elderly patients considered to be at unacceptably […]