Sudden cardiac death (SCD) is defined as a natural death due to cardiac causes, heralded by an abrupt loss of consciousness within one hour of the onset of acute symptoms. It is mostly initiated by a sudden inappropriate and extreme increase in heart rate (typically...
Cardiovascular disease is a major public health issue accounting for almost 17 million deaths per year globally. According to estimates, 40-50% of them are sudden cardiac deaths. Approximately 6 million sudden cardiac deaths are caused by ventricular tachyarrhythmias....
This Health Technology Assessment report summarises current evidence supporting the use of percutaneous heart valves in degenerative aortic valve and congenital pulmonary outflow tract disease, as compared to conservative medical therapy or traditional surgical valve...
This rapid assessment concerns the clinical effectiveness and the efficiency of innovative surgical technologies proposed for the treatment of degenerative spinal conditions: interspinous spacers and pedicle screw systems. These techniques are presented as...
Spinal surgery, including fusion and dynamic stabilisation, is one of the available treatment options for patients with symptomatic degenerative changes of the lumbar or cervical spine. The various symptoms can include local pain, radicular pain due to nerve root...
Sensorineural hearing loss is the third leading cause of disability during the adult years, according to the World Health Organization. This type of hearing loss is usually permanent, most commonly occurs gradually, and becomes worse with increasing age with clinical...
Implantable cardioverter–defibrillators (ICDs) are battery-powered implantable devices that monitor heart rhythm and deliver therapy in the form of either electric shock or antitachycardia pacing (ATP) when a life-threatening ventricular arrhythmia is detected. ICDs...
Percutaneous closure of patent foreman ovale (PFO) is one of the treatment options for patients with PFO suffering from transient ischemic attacks (TIA), cryptogenic stroke or persistent migraine. At time of writing, none of the several CE marked PFO closure devices...
Transcatheter aortic valve implantation (TAVI), also referred to as transcatheter aortic valve replacement (TAVR), is the deployment of a bioprosthesis in the aortic valve using a catheter. In contrast to traditional open-heart surgery (i.e. surgical aortic valve...
The aim of the present rapid assessment was to summarise the information on the relative effec-tiveness and safety of transcatheter implantable devices for mitral valve repair in adults with chronic mitral regurgitation (MR). Three different transcatheter therapeutic...
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