Left Atrial Appendage Closure Device With Delivery System: A Health Technology Assessment
Atrial fibrillation is a common heart disease involving electrical disturbances in the atria (the top two chambers) of the heart, which can reduce the heart’s ability to pump blood efficiently. Nonvalvular atrial fibrillation (atrial fibrillation that does not...
Retinal Prosthesis System for Advanced Retinitis Pigmentosa: A Health Technology Assessment Update
Retinitis pigmentosa is an eye disease people are born with. People who have it slowly lose their vision. The Argus II retinal implant is the only treatment approved by Health Canada for retinitis pigmentosa. A device is implanted in a patient’s eye, and it...
Magnetic Resonance-Guided Focused Ultrasound Neurosurgery for Essential Tremor: A Health Technology Assessment
Essential tremor is the most common movement disorder and most often affects the dominant hand and arm. As the tremor gets worse, it can negatively impact quality of life. Medication is the first treatment, but it does not work for many people. The next treatment...
Electronic Monitoring Systems to Assess Urinary Incontinence: A Health Technology Assessment
Urinary incontinence is the accidental leakage of urine. Assessing and managing incontinence is an important part of health care for people living in a long-term care home or geriatric inpatient setting. The effectiveness and cost of using an electronic monitoring...
Portable Ultraviolet Light Surface-Disinfecting Devices for Prevention of Hospital-Acquired Infections: A Health Technology Assessment
Hospital-acquired infections are infections that patients develop while in the hospital that were neither present nor developing when patients were admitted. In Canada about 10% of adults with short-term hospitalization have hospital-acquired infections. We studied...
Cervical Artificial Disc Replacement Versus Fusion for Cervical Degenerative Disc Disease: A Health Technology Assessment
Cervical degenerative disc disease occurs in the cervical spine (the part of the spine in the neck) when the discs between the vertebrae (the bones of the spine) start to deteriorate. It causes painful and disabling symptoms that impact people’s quality of...
Intermittent Catheters for Chronic Urinary Retention: A Health Technology Assessment
People who cannot empty their bladder on their own may develop chronic urinary retention. If not managed, this condition can lead to serious health problems. Urine that remains in the bladder for too long increases the risk of developing urinary tract...
Remote Monitoring of Implantable Cardioverter-Defibrillators, Cardiac Resynchronization Therapy and Permanent Pacemakers: A Health Technology Assessment
People suffering from certain types of heart failure, or an abnormal heart rate or rhythm, may have one ofseveral electronic devices implanted (e.g., a defibrillator or a pacemaker). However, patients require routine follow up in-clinic for clinical assessment...
The effectiveness and cost-effectiveness of dual-chamber pacemakers compared with single-chamber pacemakers for bradycardia due to atrioventricular block or sick sinus syndrome: systematic review and economic evaluation
The objective of the assessment was to estimate the effectiveness and cost-effectiveness of dualchamber pacemakers versus single-chamber atrial or single-chamber ventricular pacemakers in the treatment of bradycardia due to sick sinus syndrome...
Comparative effectiveness of MRI in breast cancer (COMICE) trial: a randomised controlled trial
MRI might improve diagnosis of breast cancer, reducing rates of reoperation. We assessed the clinical efficacy of contrast-enhanced MRI in women with primary breast cancer.We undertook an open, parallel group trial in 45 UK centres, with 1623 women aged 18 years or...
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